Reverse transcriptase: Difference between revisions

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Being the protein that gives their name to Retroviruses, Reverse Transcriptase is, in company of [[Hiv protease]] and [[Hiv integrase]], the most important part of the protein system that this type of viruses use in the process of infecting their target.
Reverse Transcriptase is a RNA-dependent DNA Polymerase, that going against the Central Dogma of Molecular Biology, transcribes ssRNA into dsDNA.


This stub was created to provide a place for an overview of reverse transcriptase, consistent with [[Proteopedia:Policy#Links_to_Wikipedia|Proteopedia Policy]]. Links intended to provide more information about reverse transcriptase should link to this page, rather than directly to Wikipedia or other sources, which should, in turn, be linked here.
==Structure==
This 2-chain protein has an usual length of 1000 residues (560 in chain A and 440 for B), the third of them involved in alpha helical secondary structure and almost a quarter in beta sheets,  


==See Also==
==See Also==


* [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Molecule of the Month (09/2002) at RCSB PDB]
* [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Molecule of the Month (09/2002) at RCSB PDB]
* List of Articles of Reverse Transcriptase at [http://www.proteopedia.org/wiki/index.php/Category:Reverse_transcriptase Proteopedia] and at [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_report.html RCSB PDB]
* List of Reverse Transcriptase articles at [http://www.proteopedia.org/wiki/index.php/Category:Reverse_transcriptase Proteopedia] and at [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_report.html RCSB PDB]
* [http://en.wikipedia.org/wiki/Reverse_transcriptase Reverse Transcriptase at Wikipedia]
* [http://en.wikipedia.org/wiki/Reverse_transcriptase Reverse Transcriptase at Wikipedia]

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Eric Martz, Daniel Moyano-Marino, Lynmarie K Thompson, Alexander Berchansky, David Canner, Jaime Prilusky, Brian Foley, Michal Harel, Amol Kapoor, Joel L. Sussman