Reverse transcriptase: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
Being the protein that gives their name to Retroviruses, Reverse Transcriptase is, in company of [[Hiv protease]] and [[Hiv integrase]], the most important part of the protein system that this type of viruses use in the process of infecting their target. | |||
Reverse Transcriptase is a RNA-dependent DNA Polymerase, that going against the Central Dogma of Molecular Biology, transcribes ssRNA into dsDNA. | |||
This | ==Structure== | ||
This 2-chain protein has an usual length of 1000 residues (560 in chain A and 440 for B), the third of them involved in alpha helical secondary structure and almost a quarter in beta sheets, | |||
==See Also== | ==See Also== | ||
* [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Molecule of the Month (09/2002) at RCSB PDB] | * [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Molecule of the Month (09/2002) at RCSB PDB] | ||
* List | * List of Reverse Transcriptase articles at [http://www.proteopedia.org/wiki/index.php/Category:Reverse_transcriptase Proteopedia] and at [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_report.html RCSB PDB] | ||
* [http://en.wikipedia.org/wiki/Reverse_transcriptase Reverse Transcriptase at Wikipedia] | * [http://en.wikipedia.org/wiki/Reverse_transcriptase Reverse Transcriptase at Wikipedia] |