3iw4: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3iw4.jpg|left|200px]]


The entry 3iw4 is ON HOLD until Paper Publication
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{{STRUCTURE_3iw4|  PDB=3iw4  |  SCENE=  }}


Authors: Stark, W., Rummel, G., Strauss, A., Cowan-Jacob, S.W.
===Crystal structure of PKC alpha in complex with NVP-AEB071===


Description: Crystal structure of PKC alpha in complex with NVP-AEB071


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{{ABSTRACT_PUBMED_19827831}}
 
==About this Structure==
3IW4 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].
 
==Reference==
<ref group="xtra">PMID:19827831</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Protein kinase C]]
[[Category: Cowan-Jacob, S W.]]
[[Category: Rummel, G.]]
[[Category: Stark, W.]]
[[Category: Strauss, A.]]
[[Category: Atp-binding]]
[[Category: Calcium]]
[[Category: Cell membrane]]
[[Category: Cytoplasm]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  4 11:01:42 2009''

Revision as of 12:01, 4 November 2009

File:3iw4.jpg

Template:STRUCTURE 3iw4

Crystal structure of PKC alpha in complex with NVP-AEB071Crystal structure of PKC alpha in complex with NVP-AEB071

Template:ABSTRACT PUBMED 19827831

About this StructureAbout this Structure

3IW4 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b

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