3jpv: Difference between revisions

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'''Unreleased structure'''
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[[Image:3jpv.jpg|left|200px]]


The entry 3jpv is ON HOLD
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{{STRUCTURE_3jpv|  PDB=3jpv |  SCENE=  }}


Authors: Filippakopoulos, P., Bullock, A.N., Fedorov, O., Akue-Gedu, R., Rossignol, E., Azzaro, S., Bain, J., Cohen, P., Prudhomme, M., Amizon, F., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Knapp, S., Structural Genomics Consortium (S
===Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand===


Description: Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand


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{{ABSTRACT_PUBMED_19788246}}
 
==About this Structure==
3JPV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JPV OCA].
 
==Reference==
<ref group="xtra">PMID:19788246</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Akue-Gedu, R.]]
[[Category: Amizon, F.]]
[[Category: Arrowsmith, C H.]]
[[Category: Azzaro, S.]]
[[Category: Bain, J.]]
[[Category: Bountra, C.]]
[[Category: Bullock, A N.]]
[[Category: Cohen, P.]]
[[Category: Delft, F von.]]
[[Category: Edwards, A.]]
[[Category: Fedorov, O.]]
[[Category: Filippakopoulos, P.]]
[[Category: Knapp, S.]]
[[Category: Moreau, P.]]
[[Category: Prudhomme, M.]]
[[Category: Rossignol, E.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Weigelt, J.]]
[[Category: Alternative initiation]]
[[Category: Atp-binding]]
[[Category: Cell membrane]]
[[Category: Cytoplasm]]
[[Category: Kinase]]
[[Category: Manganese]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Nucleus]]
[[Category: Oncogene]]
[[Category: Phosphoprotein]]
[[Category: Pim1]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Serine-threonine]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Transferase]]
[[Category: Transferase / transferase inhibitor complex]]
 
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Revision as of 14:29, 28 October 2009

File:3jpv.jpg

Template:STRUCTURE 3jpv

Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligandCrystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand

Template:ABSTRACT PUBMED 19788246

About this StructureAbout this Structure

3JPV is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Akue-Gedu R, Rossignol E, Azzaro S, Knapp S, Filippakopoulos P, Bullock AN, Bain J, Cohen P, Prudhomme M, Anizon F, Moreau P. Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors. J Med Chem. 2009 Oct 22;52(20):6369-81. PMID:19788246 doi:10.1021/jm901018f

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