1aew: Difference between revisions
New page: left|200px<br /> <applet load="1aew" size="450" color="white" frame="true" align="right" spinBox="true" caption="1aew, resolution 1.95Å" /> '''L-CHAIN HORSE APOFE... |
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==About this Structure== | ==About this Structure== | ||
1AEW is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1AEW with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb35_1.html Ferritin and Transferrin]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AEW OCA]]. | 1AEW is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 1AEW with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb35_1.html Ferritin and Transferrin]]. Structure known Active Sites: NCL, SS1, SS2 and SS3. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AEW OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: multigene family]] | [[Category: multigene family]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:37:39 2007'' | ||
Revision as of 09:32, 30 October 2007
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L-CHAIN HORSE APOFERRITIN
OverviewOverview
Mammalian ferritins are 24-mers assembled from two types of polypeptide, chain which provide the molecule with different functions. H(eavy) chains, catalyse the first step in iron storage, the oxidation of iron(II)., L(ight) chains promote the nucleation of the mineral ferrihydrite enabling, storage of iron(III) inside the protein shell. We report here the, comparison of the three-dimensional structures of recombinant human H, chain (HuHF) and horse L chain (HoLF) ferritin homopolymers, which have, been refined at 1.9 A resolution. There is 53% sequence identity between, these molecules, and the two structures are very similar, the H and L, subunit alpha-carbons superposing to within 0.5 A rms deviation with 41, water molecules in common. Nevertheless, there are significant important, ... [(full description)]
About this StructureAbout this Structure
1AEW is a [Single protein] structure of sequence from [Equus caballus] with CD as [ligand]. The following page contains interesting information on the relation of 1AEW with [Ferritin and Transferrin]. Structure known Active Sites: NCL, SS1, SS2 and SS3. Full crystallographic information is available from [OCA].
ReferenceReference
Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution., Hempstead PD, Yewdall SJ, Fernie AR, Lawson DM, Artymiuk PJ, Rice DW, Ford GC, Harrison PM, J Mol Biol. 1997 May 2;268(2):424-48. PMID:9159481
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