3ii5: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3ii5.jpg|left|200px]]


The entry 3ii5 is ON HOLD until Paper Publication
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{{STRUCTURE_3ii5|  PDB=3ii5  |  SCENE=  }}


Authors: Xu, W., Breger, D., Torres, N., Dutia, M., Powell, D., Ciszewski, G.
===The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor===


Description: The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor


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{{ABSTRACT_PUBMED_19864136}}
 
==About this Structure==
3II5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II5 OCA].
 
==Reference==
<ref group="xtra">PMID:19864136</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Breger, D.]]
[[Category: Ciszewski, G.]]
[[Category: Dutia, M.]]
[[Category: Powell, D.]]
[[Category: Torres, N.]]
[[Category: Xu, W.]]
[[Category: Acetylation]]
[[Category: Atp-binding]]
[[Category: B-raf]]
[[Category: Cardiomyopathy]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Kinase]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Proto-oncogene]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 22:29:42 2009''

Revision as of 23:29, 11 November 2009

File:3ii5.jpg

Template:STRUCTURE 3ii5

The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitorThe Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor

Template:ABSTRACT PUBMED 19864136

About this StructureAbout this Structure

3II5 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. Epub 2009 Oct 26. PMID:19864136 doi:10.1016/j.bmcl.2009.10.049

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