Sandbox Z-DNA: Difference between revisions

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 <applet load='Z-dna.pdb' size='330' frame='true' align='right' caption='Z-DNA' scene ='Sandbox_Z-DNA/Structure_of_z-dna/3' />
-Z-DNA is relatively a new structural form of a DNA which has a different structure from the more common <scene name='Sandbox_Z-DNA/Bdna/1'>B-DNA</scene> form.It is a left-handed double helix wherein the sugar-phosphate backbone has a zigzag pattern due to the alternate stacking of bases in anti-conformation and syn conformation. In Z-DNA only a minor groove is present and the major groove is absent. The residues that allow sequence-specific recognition of Z-DNA are present on the convex outer surface[[1]]. Z-DNA is thought play a role in regulation of gene expression, DNA processing events and/or genetic instability [Wang et.al .,].
+Z-DNA is relatively a new structural form of a DNA which has a different structure from the more common <scene name='Sandbox_Z-DNA/Bdna/1'>B-DNA</scene> form.It is a left-handed double helix wherein the sugar-phosphate backbone has a zigzag pattern due to the alternate stacking of bases in anti-conformation and syn conformation. In Z-DNA only a minor groove is present and the major groove is absent. The residues that allow sequence-specific recognition of Z-DNA are present on the convex outer surface<ref>PMID:12838348</ref>. Z-DNA is thought play a role in regulation of gene expression, DNA processing events and/or genetic instability [Wang et.al .,].
 == Structure ==