Sandbox Z-DNA: Difference between revisions
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<applet load='Z-dna.pdb' size='330' frame='true' align='right' caption='Z-DNA' scene ='Sandbox_Z-DNA/Structure_of_z-dna/3' /> | <applet load='Z-dna.pdb' size='330' frame='true' align='right' caption='Z-DNA' scene ='Sandbox_Z-DNA/Structure_of_z-dna/3' /> | ||
Z-DNA is relatively a new structural form of a DNA which has a different structure from the more common B-DNA form.It is a left-handed double helix wherein the sugar-phosphate backbone has a zigzag pattern due to the alternate stacking of bases in anti-conformation and syn conformation. In Z-DNA only a minor groove is present and the major groove is absent. The residues that allow sequence-specific recognition of Z-DNA are present on the convex outer surface [Herbert et.al.,]. Z-DNA is thought play a role in regulation of gene expression, DNA processing events and/or genetic instability [Wang et.al .,]. | Z-DNA is relatively a new structural form of a DNA which has a different structure from the more common <scene name='Sandbox_Z-DNA/Bdna/1'>B-DNA</scene> form.It is a left-handed double helix wherein the sugar-phosphate backbone has a zigzag pattern due to the alternate stacking of bases in anti-conformation and syn conformation. In Z-DNA only a minor groove is present and the major groove is absent. The residues that allow sequence-specific recognition of Z-DNA are present on the convex outer surface [Herbert et.al.,]. Z-DNA is thought play a role in regulation of gene expression, DNA processing events and/or genetic instability [Wang et.al .,]. | ||
== Structure == | == Structure == | ||