Nitric Oxide Synthase: Difference between revisions
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<applet load='2g6h' size='300' color='white' frame='true' align='right' caption='Oxygenase domain' /> | <applet load='2g6h' size='300' color='white' frame='true' align='right' caption='Oxygenase domain' /> | ||
The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate <scene name='Nitric_oxide_synthase/Nos_oxygenase_arg/ | The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate <scene name='Nitric_oxide_synthase/Nos_oxygenase_arg/3'>L-Arginine</scene> ([http://en.wikipedia.org/wiki/Arginine Arginine]) which is converted into citruline and NO (explained in details below). The domain has three cofactors bound: | ||
<scene name='Nitric_oxide_synthase/Nos_oxygenase_bh4/1'>H4B</scene> ([http://en.wikipedia.org/wiki/BH4 (6R).5,6,7,8-Tetrahydrobiopterin]) | <scene name='Nitric_oxide_synthase/Nos_oxygenase_bh4/1'>H4B</scene> ([http://en.wikipedia.org/wiki/BH4 (6R).5,6,7,8-Tetrahydrobiopterin]) | ||
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<scene name='Nitric_oxide_synthase/Nos_oxygenase_heme/1'>Heme</scene> ([http://en.wikipedia.org/wiki/Heme Heme]) | <scene name='Nitric_oxide_synthase/Nos_oxygenase_heme/1'>Heme</scene> ([http://en.wikipedia.org/wiki/Heme Heme]) | ||
<scene name='Nitric_oxide_synthase/Nos_oxygenase_zinc/ | <scene name='Nitric_oxide_synthase/Nos_oxygenase_zinc/4'>Zinc ion</scene> | ||