Nitric Oxide Synthase: Difference between revisions

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== The Oxygenase domain of NOS ==
== The Oxygenase domain of NOS ==
{{STRUCTURE_2g6h|PDB=2g6h|SCENE=Nitric_oxide_synthase/Nos_oxygenase_med_cofaktore/1}}
 
<applet load='2g6h' size='300' color='white' frame='true' align='right' caption='Oxygenase domain' />
 
 
 


The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate L<scene name='Nitric_oxide_synthase/Nos_oxygenase_arg/1'>Arginine</scene> ([http://en.wikipedia.org/wiki/Arginine Arginine]) which is converted into citruline and NO (explained in details below). The domain has three cofactors bound:  
The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate L<scene name='Nitric_oxide_synthase/Nos_oxygenase_arg/1'>Arginine</scene> ([http://en.wikipedia.org/wiki/Arginine Arginine]) which is converted into citruline and NO (explained in details below). The domain has three cofactors bound:  

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Michael Skovbo Windahl, Sara Toftegaard Petersen, Mathilde Thomsen, Mette Trauelsen, Eran Hodis, Jaime Prilusky, Karl Oberholser, Alexander Berchansky, Michal Harel, Ann Taylor