Complex III of Electron Transport Chain: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Karl Oberholser, Eran Hodis, Jaime Prilusky, Alexander Berchansky, Michal Harel

@@ Line 26: / Line 26: @@
 ==View Interior of Q Binding Sites==
-<applet load='1bgy_modified.pdb' size='400' frame='true' align='right' scene ='Complex_III_of_Electron_Transport_Chain/1bgy_qsite_surfaces/3'  />The applet on the right shows the interior cavities of Complex III with the four Q sites labeled.<ref name=1BGYmodified/>  (<scene name='Complex_III_of_Electron_Transport_Chain/1bgy_qsite_surfaces/3'>Reset initial scene.</scene>)  The PDB file used to generate the display has no cofactors binding at these sites so they are empty. After turning on the Slicer observe that as the surface is rotated
+<applet load='1bgy_modified.pdb' size='400' frame='true' align='right' scene ='Complex_III_of_Electron_Transport_Chain/1bgy_qsite_surfaces/4'  />The applet on the right shows the surface of interior cavities of Complex III with the four substrate binding sites labeled.<ref name=1BGYmodified/>  (<scene name='Complex_III_of_Electron_Transport_Chain/1bgy_qsite_surfaces/3'>Reset initial scene.</scene>)  The PDB file used to generate the display has no cofactors binding at these sites so they are empty. After turning on the Slicer observe that
 <jmol>
 <jmolButton>
@@ Line 35: / Line 35: @@
 </jmol>
-its interior is exposed and that the binding sites are joined by connecting interior chambers.
+as the surface rotates its interior is exposed and that the empty binding sites are joined by connecting interior channels. These channels permit the UQ that is formed in Q<sub>p</sub> to diffuse to Q<sub>n</sub> where it is reduced to UQH<sub>2</sub>, and in turn the UQH<sub>2</sub> can diffuse to a Q<sub>p</sub> where it is oxidized to UQ.
 ==Notes and References==
 <references/>