3gnv: Difference between revisions

Revision as of 11:20, 21 October 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3gnv.jpg

Template:STRUCTURE 3gnv

HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1bHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b

Template:ABSTRACT PUBMED 19507864

About this StructureAbout this Structure

3GNV is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548

Page seeded by OCA on Wed Oct 21 10:20:17 2009

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548

[xtra 1]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3gnv.jpg|left|200px]]
-The entry 3gnv is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3gnv", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3gnv|  PDB=3gnv  |  SCENE=  }}
-Authors: De Bondt, H., Nyanguile, O.
+===HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b===
-Description: HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 30 08:44:31 2009''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_19507864}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 19507864 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_19507864}}
+==About this Structure==
+GNV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNV OCA].
+==Reference==
+<ref group="xtra">PMID:19507864</ref><references group="xtra"/>
+[[Category: RNA-directed RNA polymerase]]
+[[Category: Viruses]]
+[[Category: Bondt, H De.]]
+[[Category: Nyanguile, O.]]
+[[Category: 1 5-benzodiazepine]]
+[[Category: Acetylation]]
+[[Category: Apoptosis]]
+[[Category: Atp-binding]]
+[[Category: Capsid protein]]
+[[Category: Cell membrane]]
+[[Category: Cytoplasm]]
+[[Category: Endoplasmic reticulum]]
+[[Category: Envelope protein]]
+[[Category: Fusion protein]]
+[[Category: Glycoprotein]]
+[[Category: Helicase]]
+[[Category: Hepatitis c virus]]
+[[Category: Host-virus interaction]]
+[[Category: Hydrolase]]
+[[Category: Interferon antiviral system evasion]]
+[[Category: Lipid droplet]]
+[[Category: Lipoprotein]]
+[[Category: Membrane]]
+[[Category: Metal-binding]]
+[[Category: Mitochondrion]]
+[[Category: Multifunctional enzyme]]
+[[Category: Ns5b]]
+[[Category: Nucleotide-binding]]
+[[Category: Nucleotidyltransferase]]
+[[Category: Nucleus]]
+[[Category: Oncogene]]
+[[Category: Palmitate]]
+[[Category: Phosphoprotein]]
+[[Category: Polymerase]]
+[[Category: Protease]]
+[[Category: Ribonucleoprotein]]
+[[Category: Rna replication]]
+[[Category: Rna-binding]]
+[[Category: Rna-directed rna polymerase]]
+[[Category: Secreted]]
+[[Category: Serine protease]]
+[[Category: Sh3-binding]]
+[[Category: Sulfone]]
+[[Category: Thiol protease]]
+[[Category: Transcription]]
+[[Category: Transcription regulation]]
+[[Category: Transferase]]
+[[Category: Transmembrane]]
+[[Category: Ubl conjugation]]
+[[Category: Viral nucleoprotein]]
+[[Category: Virion]]
+[[Category: Zinc]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:20:17 2009''