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| {{STRUCTURE_3f82| PDB=3f82 | SCENE= }}
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| ===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide===
| | Authors: Sack, J. |
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| | Description: Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide |
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| (as it appears on PubMed at http://www.pubmed.gov), where 19260711 is the PubMed ID number.
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| {{ABSTRACT_PUBMED_19260711}}
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| ==Disease==
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| Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
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| ==About this Structure==
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| 3F82 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F82 OCA].
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| ==Reference==
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| <ref group="xtra">PMID:19260711</ref><references group="xtra"/>
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| [[Category: Homo sapiens]]
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| [[Category: Receptor protein-tyrosine kinase]]
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| [[Category: Sack, J.]]
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| [[Category: Alternative splicing]]
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| [[Category: Atp-binding]]
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| [[Category: Glycoprotein]]
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| [[Category: Grb2]]
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| [[Category: Membrane]]
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| [[Category: Nucleotide-binding]]
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| [[Category: Phosphoprotein]]
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| [[Category: Proto-oncogene]]
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| [[Category: Receptor tyrosine kinase]]
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| [[Category: Shc]]
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| [[Category: Signal transduction]]
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| [[Category: Transferase]]
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| [[Category: Transmembrane]]
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| [[Category: Tyrosine-protein kinase]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 2 15:30:14 2009'' | |
Unreleased structure
The entry 3f82 is ON HOLD until Paper Publication
Authors: Sack, J.
Description: Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Page seeded by OCA on Thu Apr 9 12:16:15 2009