Triose Phosphate Isomerase: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 === Acid Base Catalysis ===
+TPI carries out the isomerization reaction through acid base chemistry involving two residues <scene name='Triose_Phosphate_Isomerase/residues/1'>acid base</scene>,
-<scene name='Triose_Phosphate_Isomerase/Acid-base_residues/1'>acid base</scene>
+Glutamate 165 plays the role of the general acid-base catalyst in a proton abstraction mechanism as it abstracts a proton from carbon 1, which then donates it to carbon 2. Glutamate 165 requires Histidine 95, the general acid
-Glutamate 165 plays the role of the general acid-base catalyst in a proton abstraction mechanism as it abstractluts a proton from carebon 1, which then donates it to carbon 2. Glutamate 165 requires Histidine 95, the general acid
 [[Image:TPI mechanism.jpg]]