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| <B>This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!</B>
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| Quoc Hung Pham 3/3/09
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| <applet load='1H9Z' size='300' frame='true' align='right' />
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| ==Name==
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| Human Serum Albumin
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| ==About this Structure==
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| This is the Human Serum Albumin(HSA),it has <scene name='Sandbox13/Alpha_helices/1'>alpha helices</scene> (shown in red), <scene name='Sandbox13/Beta_sheets/1'>beta sheets</scene> (shown in blue), and the <scene name='Sandbox13/Hydrophobic/1'>hydrophobic</scene> parts. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics.
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| Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001
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