1sl3: Difference between revisions
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[[Image:1sl3.png|left|200px]] | [[Image:1sl3.png|left|200px]] | ||
{{STRUCTURE_1sl3| PDB=1sl3 | SCENE= }} | {{STRUCTURE_1sl3| PDB=1sl3 | SCENE= }} | ||
===crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor=== | ===crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor=== | ||
{{ABSTRACT_PUBMED_15163182}} | {{ABSTRACT_PUBMED_15163182}} | ||
==About this Structure== | ==About this Structure== | ||
[[1sl3]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SL3 OCA]. | |||
==See Also== | |||
*[[Hirudin|Hirudin]] | |||
*[[Thrombin|Thrombin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:015163182</ref><references group="xtra"/> | ||
[[Category: Hirudo medicinalis]] | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 47: | Line 40: | ||
[[Category: Williams, P D.]] | [[Category: Williams, P D.]] | ||
[[Category: Young, M B.]] | [[Category: Young, M B.]] | ||
[[Category: Blood clotting]] | |||
[[Category: Hydrolase-inhibitor complex]] | |||
[[Category: Thrombin inhibitor complex]] | [[Category: Thrombin inhibitor complex]] | ||
Revision as of 19:15, 27 July 2012
crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitorcrystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor
Template:ABSTRACT PUBMED 15163182
About this StructureAbout this Structure
1sl3 is a 2 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG. Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors. J Med Chem. 2004 Jun 3;47(12):2995-3008. PMID:15163182 doi:10.1021/jm030303e
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Hirudo medicinalis
- Homo sapiens
- Thrombin
- Barrow, J C.
- Bohn, D.
- Clayton, F C.
- Cook, J J.
- Glass, K L.
- Krueger, J A.
- Kuo, L C.
- Lewis, S D.
- Lucas, B J.
- Lundell, G F.
- McMasters, D R.
- Miller-Stein, C.
- Newton, C L.
- Pellicore, J M.
- Pietrak, B L.
- Rittle, K E.
- Selnick, H G.
- Stauffer, K J.
- Vacca, J P.
- Williams, P D.
- Young, M B.
- Blood clotting
- Hydrolase-inhibitor complex
- Thrombin inhibitor complex