1rd3: Difference between revisions

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{{Seed}}
[[Image:1rd3.png|left|200px]]
[[Image:1rd3.png|left|200px]]


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{{STRUCTURE_1rd3|  PDB=1rd3  |  SCENE=  }}  
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===2.5A Structure of Anticoagulant Thrombin Variant E217K===
===2.5A Structure of Anticoagulant Thrombin Variant E217K===


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==Disease==
==About this Structure==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
[[1rd3]] is a 4 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RD3 OCA].


==About this Structure==
==See Also==
1RD3 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RD3 OCA].
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:15075325</ref><references group="xtra"/>
<ref group="xtra">PMID:015075325</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Myles, T.]]
[[Category: Myles, T.]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:02:59 2009''

Revision as of 18:16, 27 July 2012

File:1rd3.png

Template:STRUCTURE 1rd3

2.5A Structure of Anticoagulant Thrombin Variant E217K2.5A Structure of Anticoagulant Thrombin Variant E217K

Template:ABSTRACT PUBMED 15075325

About this StructureAbout this Structure

1rd3 is a 4 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery. J Biol Chem. 2004 Jun 18;279(25):26387-94. Epub 2004 Apr 9. PMID:15075325 doi:http://dx.doi.org/10.1074/jbc.M402364200
  2. ↑ Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551

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