2g22: Difference between revisions

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{{Seed}}
[[Image:2g22.png|left|200px]]
[[Image:2g22.png|left|200px]]


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{{STRUCTURE_2g22|  PDB=2g22  |  SCENE=  }}  
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===Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring===
===Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring===


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{{ABSTRACT_PUBMED_16480874}}
{{ABSTRACT_PUBMED_16480874}}


==Disease==
==About this Structure==
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]]
[[2g22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G22 OCA].


==About this Structure==
==See Also==
2G22 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G22 OCA].
*[[Renin|Renin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16480874</ref><references group="xtra"/>
<ref group="xtra">PMID:016480874</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Renin]]
[[Category: Renin]]
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[[Category: Mcconnella, P.]]
[[Category: Mcconnella, P.]]
[[Category: Zhanga, E.]]
[[Category: Zhanga, E.]]
[[Category: Hydrolase]]
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:11:50 2009''

Revision as of 00:36, 21 October 2012

File:2g22.png

Template:STRUCTURE 2g22

Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" RingKetopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring

Template:ABSTRACT PUBMED 16480874

About this StructureAbout this Structure

2g22 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:http://dx.doi.org/10.1016/j.bmcl.2006.01.084

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