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{{Seed}}
[[Image:3bwm.png|left|200px]]
[[Image:3bwm.png|left|200px]]


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===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC===
===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC===


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{{ABSTRACT_PUBMED_18486144}}
{{ABSTRACT_PUBMED_18486144}}
==Disease==
Known disease associated with this structure: Panic disorder, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]], Schizophrenia, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]]


==About this Structure==
==About this Structure==
3BWM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWM OCA].  
[[3bwm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWM OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18486144</ref><references group="xtra"/>
<ref group="xtra">PMID:018486144</ref><references group="xtra"/>
[[Category: Catechol O-methyltransferase]]
[[Category: Catechol O-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Catecholamine metabolism]]
[[Category: Catecholamine metabolism]]
[[Category: Comt]]
[[Category: Comt]]
[[Category: Cytoplasm]]
[[Category: Dnc]]
[[Category: Dnc]]
[[Category: Magnesium]]
[[Category: Magnesium]]
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[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Neurotransmitter degradation]]
[[Category: Neurotransmitter degradation]]
[[Category: Polymorphism]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: S-adenosyl-l-methionine]]
[[Category: S-adenosyl-l-methionine]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:10:43 2009''

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