2fvd: Difference between revisions

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[[Image:2fvd.png|left|200px]]
[[Image:2fvd.png|left|200px]]


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{{STRUCTURE_2fvd|  PDB=2fvd  |  SCENE=  }}  
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===Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor===
===Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor===


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{{ABSTRACT_PUBMED_17064073}}
{{ABSTRACT_PUBMED_17064073}}


==About this Structure==
==About this Structure==
2FVD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVD OCA].  
[[2fvd]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVD OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]


==Reference==
==Reference==
<ref group="xtra">PMID:17064073</ref><references group="xtra"/>
<ref group="xtra">PMID:017064073</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Lukacs, C M.]]
[[Category: Lukacs, C M.]]
[[Category: Cdk2 ligand]]
[[Category: Cdk2 ligand]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:11:43 2009''

Revision as of 14:31, 27 July 2012

File:2fvd.png

Template:STRUCTURE 2fvd

Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitorCyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor

Template:ABSTRACT PUBMED 17064073

About this StructureAbout this Structure

2fvd is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-diflu oro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J Med Chem. 2006 Nov 2;49(22):6549-60. PMID:17064073 doi:10.1021/jm0606138

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