1nvw: Difference between revisions

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{{Seed}}
[[Image:1nvw.png|left|200px]]
[[Image:1nvw.png|left|200px]]


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===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS===
===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS===


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{{ABSTRACT_PUBMED_12628188}}


==Disease==
==About this Structure==
Known disease associated with this structure: Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]]
[[1nvw]] is a 3 chain structure of [[GTPase HRas]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVW OCA].


==About this Structure==
==See Also==
1NVW is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVW OCA].
*[[GTPase HRas|GTPase HRas]]


==Reference==
==Reference==
<ref group="xtra">PMID:12628188</ref><references group="xtra"/>
<ref group="xtra">PMID:012628188</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bar-Sagi, D.]]
[[Category: Bar-Sagi, D.]]
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[[Category: Guanine-nucleotide releasing factor]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
 
[[Category: Signaling protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:54:58 2009''

Revision as of 10:01, 27 July 2012

File:1nvw.png

Template:STRUCTURE 1nvw

Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOSStructural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

Template:ABSTRACT PUBMED 12628188

About this StructureAbout this Structure

1nvw is a 3 chain structure of GTPase HRas with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188

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