1s3w: Difference between revisions

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{{Seed}}
[[Image:1s3w.png|left|200px]]
[[Image:1s3w.png|left|200px]]


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{{ABSTRACT_PUBMED_15039552}}
{{ABSTRACT_PUBMED_15039552}}


==Disease==
==About this Structure==
Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126060 126060]]
[[1s3w]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3W OCA].


==About this Structure==
==See Also==
1S3W is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3W OCA].
*[[Dihydrofolate reductase]]


==Reference==
==Reference==
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[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Inhibitor complex]]
[[Category: Inhibitor complex]]
[[Category: Oxidoreductase]]
[[Category: Stereochemistry]]
[[Category: Stereochemistry]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:58:02 2009''

Revision as of 11:25, 26 December 2010

File:1s3w.png

Template:STRUCTURE 1s3w

Structure Determination of Tetrahydroquinazoline Antifoaltes in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and StereochemistryStructure Determination of Tetrahydroquinazoline Antifoaltes in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry

Template:ABSTRACT PUBMED 15039552

About this StructureAbout this Structure

1s3w is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):646-55. Epub 2004, Mar 23. PMID:15039552 doi:http://dx.doi.org/10.1107/S0907444904002094

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