1jm7: Difference between revisions

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{{Seed}}
[[Image:1jm7.png|left|200px]]
[[Image:1jm7.png|left|200px]]


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{{STRUCTURE_1jm7|  PDB=1jm7  |  SCENE=  }}  
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===Solution structure of the BRCA1/BARD1 RING-domain heterodimer===
===Solution structure of the BRCA1/BARD1 RING-domain heterodimer===


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{{ABSTRACT_PUBMED_11573085}}
{{ABSTRACT_PUBMED_11573085}}
==Disease==
Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601593 601593]]


==About this Structure==
==About this Structure==
1JM7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JM7 OCA].  
[[1jm7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JM7 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:11573085</ref><references group="xtra"/>
<ref group="xtra">PMID:011573085</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Brzovic, P S.]]
[[Category: Brzovic, P S.]]
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[[Category: Klevit, R E.]]
[[Category: Klevit, R E.]]
[[Category: Rajagopal, P.]]
[[Category: Rajagopal, P.]]
[[Category: Antitumor]]
[[Category: Bard1]]
[[Category: Bard1]]
[[Category: Brca1]]
[[Category: Brca1]]
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[[Category: Ubiquitin ligase]]
[[Category: Ubiquitin ligase]]
[[Category: Zinc-binding protein]]
[[Category: Zinc-binding protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:10:38 2009''

Revision as of 14:20, 5 December 2012

File:1jm7.png

Template:STRUCTURE 1jm7

Solution structure of the BRCA1/BARD1 RING-domain heterodimerSolution structure of the BRCA1/BARD1 RING-domain heterodimer

Template:ABSTRACT PUBMED 11573085

About this StructureAbout this Structure

1jm7 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833

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