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3c2i: Difference between revisions

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[[Image:3c2i.png|left|200px]]
[[Image:3c2i.png|left|200px]]


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{{STRUCTURE_3c2i|  PDB=3c2i  |  SCENE=  }}  
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===The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF===
===The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF===


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{{ABSTRACT_PUBMED_18313390}}


==Disease==
==About this Structure==
Known disease associated with this structure: Angelman syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Encephalopathy, neonatal severe OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Mental retardation, X-linked, Lubs type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Mental retardation, X-linked, syndromic 13 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Rett syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Rett syndrome, preserved speech variant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]], Autism, susceptibility to, X-linked-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300005 300005]]
[[3c2i]] is a 3 chain structure of [[Methyl CpG Binding Protein 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C2I OCA].  


==About this Structure==
==See Also==
3C2I is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C2I OCA].
*[[Methyl CpG Binding Protein 2|Methyl CpG Binding Protein 2]]


==Reference==
==Reference==
<ref group="xtra">PMID:18313390</ref><references group="xtra"/>
<ref group="xtra">PMID:018313390</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bird, A P.]]
[[Category: Bird, A P.]]
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[[Category: Schmiedeberg, L.]]
[[Category: Schmiedeberg, L.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
[[Category: Alternative splicing]]
[[Category: Asx-st-motif]]
[[Category: Asx-st-motif]]
[[Category: Chromosomal rearrangement]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-methylated dna complex]]
[[Category: Protein-methylated dna complex]]
[[Category: Repressor]]
[[Category: Repressor]]
[[Category: Transcription regulator]]
[[Category: Transcription regulator]]
[[Category: Water mediated recognition]]
[[Category: Water mediated recognition]]
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