2gtw: Difference between revisions

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{{Seed}}
[[Image:2gtw.png|left|200px]]
[[Image:2gtw.png|left|200px]]


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===Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution===
===Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution===


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{{ABSTRACT_PUBMED_17719062}}


==Disease==
==About this Structure==
Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Ankylosing spondylitis, susceptibility to, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Stevens-Johnson syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142800 142800]], Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
[[2gtw]] is a 6 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTW OCA].


==About this Structure==
==See Also==
2GTW is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTW OCA].
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Major histocompatibility complex|Major histocompatibility complex]]


==Reference==
==Reference==
<ref group="xtra">PMID:17719062</ref><references group="xtra"/>
<ref group="xtra">PMID:017719062</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baker, B M.]]
[[Category: Baker, B M.]]
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[[Category: Cancer vaccine]]
[[Category: Cancer vaccine]]
[[Category: Hla-a2]]
[[Category: Hla-a2]]
[[Category: Immune system]]
[[Category: Melan-a/mart-1 peptide]]
[[Category: Melan-a/mart-1 peptide]]
[[Category: Melanoma]]
[[Category: Melanoma]]
[[Category: Mhc class i]]
[[Category: Mhc class i]]
[[Category: Nonapeptide]]
[[Category: Nonapeptide]]
[[Category: X-ray crystallography]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:19:02 2009''

Revision as of 18:23, 26 July 2012

File:2gtw.png

Template:STRUCTURE 2gtw

Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitutionHuman Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution

Template:ABSTRACT PUBMED 17719062

About this StructureAbout this Structure

2gtw is a 6 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025

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