2aei: Difference between revisions

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[[Image:2aei.png|left|200px]]
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===Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid===
===Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid===


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{{ABSTRACT_PUBMED_16125385}}
{{ABSTRACT_PUBMED_16125385}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
[[2aei]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEI OCA].


==About this Structure==
==See Also==
2AEI is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEI OCA].
*[[Factor VIIa|Factor VIIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:16125385</ref><references group="xtra"/>
<ref group="xtra">PMID:016125385</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Enzyme inhibitor complex]]
[[Category: Enzyme inhibitor complex]]
[[Category: Gla]]
[[Category: Gla]]
[[Category: Hydrolase]]
[[Category: Pyridine]]
[[Category: Pyridine]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Thrombosis]]
[[Category: Thrombosis]]
[[Category: Tissue factor]]
[[Category: Tissue factor]]
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