3drs: Difference between revisions
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[[Image:3drs.png|left|200px]] | [[Image:3drs.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[3drs]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRS OCA]. | |||
==See Also== | |||
*[[Reverse transcriptase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Nucleotidyltrasferase]] | [[Category: Nucleotidyltrasferase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 01:47, 27 December 2010
HIV reverse transcriptase K103N mutant in complex with inhibitor R8DHIV reverse transcriptase K103N mutant in complex with inhibitor R8D
Template:ABSTRACT PUBMED 18826204
About this StructureAbout this Structure
3drs is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Reid JC, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses. J Med Chem. 2008 Oct 1. PMID:18826204 doi:10.1021/jm800856c