2c1e: Difference between revisions
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[[Image:2c1e.png|left|200px]] | [[Image:2c1e.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[2c1e]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C1E OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016970398</ref><ref group="xtra">PMID:019465933</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Grutter, M G.]] | [[Category: Grutter, M G.]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Aza-asp]] | |||
[[Category: Aza-peptide]] | [[Category: Aza-peptide]] | ||
[[Category: Clan cd]] | [[Category: Clan cd]] | ||
[[Category: Cpp32]] | [[Category: Cpp32]] | ||
[[Category: Cysteine-protease]] | [[Category: Cysteine-protease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Michael acceptor | [[Category: Michael acceptor]] | ||
[[Category: Thiol protease | [[Category: Thiol protease]] | ||
[[Category: Yama]] | [[Category: Yama]] | ||
[[Category: Zymogen]] | |||
Revision as of 10:02, 20 July 2011
CRYSTAL STRUCTURES OF CASPASE-3 IN COMPLEX WITH AZA-PEPTIDE MICHAEL ACCEPTOR INHIBITORS.CRYSTAL STRUCTURES OF CASPASE-3 IN COMPLEX WITH AZA-PEPTIDE MICHAEL ACCEPTOR INHIBITORS.
Template:ABSTRACT PUBMED 16970398
About this StructureAbout this Structure
2c1e is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grutter MG, Powers JC. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10. J Med Chem. 2006 Sep 21;49(19):5728-49. PMID:16970398 doi:http://dx.doi.org/10.1021/jm0601405
- ↑ Shen A, Lupardus PJ, Albrow VE, Guzzetta A, Powers JC, Garcia KC, Bogyo M. Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol. 2009 Jul;5(7):469-78. PMID:19465933 doi:10.1038/nchembio.178