3cxw: Difference between revisions

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{{Seed}}
[[Image:3cxw.png|left|200px]]
[[Image:3cxw.png|left|200px]]


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===Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I===
===Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I===


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==About this Structure==
==About this Structure==
3CXW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXW OCA].  
[[3cxw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXW OCA].  
 
==Reference==
<ref group="xtra">PMID:022136433</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Alternative initiation]]
[[Category: Alternative initiation]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cytoplasm]]
[[Category: Host-virus interaction]]
[[Category: Host-virus interaction]]
[[Category: Kinase]]
[[Category: Kinase]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Pim1]]
[[Category: Pim1]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: Serine-threonine]]
[[Category: Serine-threonine]]
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[[Category: Virion]]
[[Category: Virion]]
[[Category: Virulence]]
[[Category: Virulence]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:07:41 2009''

Revision as of 13:05, 18 January 2012

File:3cxw.png

Template:STRUCTURE 3cxw

Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand ICrystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I

Template:ABSTRACT PUBMED 22136433

About this StructureAbout this Structure

3cxw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. 7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes. J Med Chem. 2012 Jan 12;55(1):403-13. Epub 2012 Jan 3. PMID:22136433 doi:10.1021/jm201286z

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