1w22: Difference between revisions

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[[Image:1w22.png|left|200px]]
[[Image:1w22.png|left|200px]]


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===CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8===
===CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8===


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{{ABSTRACT_PUBMED_15477595}}


==About this Structure==
==About this Structure==
1W22 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W22 OCA].  
[[1w22]] is a 2 chain structure of [[Histone deacetylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W22 OCA].  
 
==See Also==
*[[Histone deacetylase|Histone deacetylase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15477595</ref><references group="xtra"/>
<ref group="xtra">PMID:015477595</ref><ref group="xtra">PMID:019053282</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Casavola, E Caroli.]]
[[Category: Casavola, E Caroli.]]
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[[Category: Nuclear protein]]
[[Category: Nuclear protein]]
[[Category: Repressor]]
[[Category: Repressor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:12:11 2009''

Revision as of 08:27, 26 July 2012

File:1w22.png

Template:STRUCTURE 1w22

CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8

Template:ABSTRACT PUBMED 15477595

About this StructureAbout this Structure

1w22 is a 2 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Vannini A, Volpari C, Filocamo G, Casavola EC, Brunetti M, Renzoni D, Chakravarty P, Paolini C, De Francesco R, Gallinari P, Steinkuhler C, Di Marco S. Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15064-9. Epub 2004 Oct 11. PMID:15477595
  2. ↑ Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW. Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry. 2008 Dec 23;47(51):13554-63. PMID:19053282 doi:10.1021/bi801610c

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