1gj5: Difference between revisions
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[[Image:1gj5.png|left|200px]] | [[Image:1gj5.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[1gj5]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ5 OCA]. | |||
==See Also== | |||
*[[Hirudin]] | |||
==Reference== | ==Reference== | ||
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[[Category: Sprengeler, P A.]] | [[Category: Sprengeler, P A.]] | ||
[[Category: Verner, E.]] | [[Category: Verner, E.]] | ||
[[Category: Blood clotting]] | |||
[[Category: Hydrolase]] | |||
[[Category: Oxyanion hole water]] | [[Category: Oxyanion hole water]] | ||
[[Category: Shift of pka of his57]] | [[Category: Shift of pka of his57]] | ||
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[[Category: Very short hydrogen bond]] | [[Category: Very short hydrogen bond]] | ||
[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
Revision as of 05:23, 27 December 2010
SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGNSELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN
Template:ABSTRACT PUBMED 11731301
About this StructureAbout this Structure
1gj5 is a 3 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Allen, D.
- Breitenbucher, J G.
- Hui, H.
- Katz, B A.
- Luong, C.
- Mackman, R L.
- Martelli, A.
- McGee, D.
- Spencer, J R.
- Sprengeler, P A.
- Verner, E.
- Blood clotting
- Hydrolase
- Oxyanion hole water
- Shift of pka of his57
- Specificity
- Structure-based drug design
- Three-centered
- Trypsin
- Urokinase
- Very short hydrogen bond
- Zn+2-mediated inhibition