1t83: Difference between revisions
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{{STRUCTURE_1t83| PDB=1t83 | SCENE= }} | {{STRUCTURE_1t83| PDB=1t83 | SCENE= }} | ||
===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)=== | ===CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)=== | ||
{{ABSTRACT_PUBMED_11297532}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FCG3B_HUMAN FCG3B_HUMAN]] Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. | |||
==About this Structure== | ==About this Structure== | ||
[[1t83]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1iis 1iis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T83 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:011297532</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fridman, W H.]] | [[Category: Fridman, W H.]] | ||
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[[Category: Fcgriii]] | [[Category: Fcgriii]] | ||
[[Category: Igg1]] | [[Category: Igg1]] | ||
[[Category: Immune system]] | |||
[[Category: Immunoglobulin]] | [[Category: Immunoglobulin]] | ||