2r7b: Difference between revisions
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[[Image:2r7b.png|left|200px]] | [[Image:2r7b.png|left|200px]] | ||
{{STRUCTURE_2r7b| PDB=2r7b | SCENE= }} | {{STRUCTURE_2r7b| PDB=2r7b | SCENE= }} | ||
===Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor=== | ===Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor=== | ||
{{ABSTRACT_PUBMED_17941624}} | {{ABSTRACT_PUBMED_17941624}} | ||
==About this Structure== | ==About this Structure== | ||
[[2r7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7B OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017941624</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| Line 31: | Line 19: | ||
[[Category: Pdk1]] | [[Category: Pdk1]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 22:17, 7 January 2013
Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitorCrystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor
Template:ABSTRACT PUBMED 17941624
About this StructureAbout this Structure
2r7b is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Gopalsamy A, Shi M, Boschelli DH, Williamson R, Olland A, Hu Y, Krishnamurthy G, Han X, Arndt K, Guo B. Discovery of dibenzo[c,f][2,7]naphthyridines as potent and selective 3-phosphoinositide-dependent kinase-1 inhibitors. J Med Chem. 2007 Nov 15;50(23):5547-9. Epub 2007 Oct 17. PMID:17941624 doi:10.1021/jm070851i