2hs1: Difference between revisions

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[[Image:2hs1.png|left|200px]]
[[Image:2hs1.png|left|200px]]


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===Ultra-high resolution X-ray crystal structure of HIV-1 protease V32I mutant with TMC114 (darunavir) inhibitor===
===Ultra-high resolution X-ray crystal structure of HIV-1 protease V32I mutant with TMC114 (darunavir) inhibitor===


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{{ABSTRACT_PUBMED_16962136}}


==About this Structure==
==About this Structure==
2HS1 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS1 OCA].  
[[2hs1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS1 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:16962136</ref><references group="xtra"/>
<ref group="xtra">PMID:016962136</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Kovalevsky, A Y.]]
[[Category: Kovalevsky, A Y.]]
[[Category: Weber, I T.]]
[[Category: Weber, I T.]]
[[Category: Hydrolase]]
[[Category: Ultra-high resolution active site surface binding site]]
[[Category: Ultra-high resolution active site surface binding site]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:50:27 2009''

Revision as of 21:03, 7 January 2013

File:2hs1.png

Template:STRUCTURE 2hs1

Ultra-high resolution X-ray crystal structure of HIV-1 protease V32I mutant with TMC114 (darunavir) inhibitorUltra-high resolution X-ray crystal structure of HIV-1 protease V32I mutant with TMC114 (darunavir) inhibitor

Template:ABSTRACT PUBMED 16962136

About this StructureAbout this Structure

2hs1 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007

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