2oah: Difference between revisions
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[[Image:2oah.png|left|200px]] | [[Image:2oah.png|left|200px]] | ||
{{STRUCTURE_2oah| PDB=2oah | SCENE= }} | {{STRUCTURE_2oah| PDB=2oah | SCENE= }} | ||
===Crystal Structure of Human Beta Secretase Complexed with inhibitor=== | ===Crystal Structure of Human Beta Secretase Complexed with inhibitor=== | ||
{{ABSTRACT_PUBMED_17257835}} | {{ABSTRACT_PUBMED_17257835}} | ||
==About this Structure== | ==About this Structure== | ||
[[2oah]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OAH OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017257835</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Bace]] | [[Category: Bace]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 15:47, 25 July 2012
Crystal Structure of Human Beta Secretase Complexed with inhibitorCrystal Structure of Human Beta Secretase Complexed with inhibitor
Template:ABSTRACT PUBMED 17257835
About this StructureAbout this Structure
2oah is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Stauffer SR, Stanton MG, Gregro AR, Steinbeiser MA, Shaffer JR, Nantermet PG, Barrow JC, Rittle KE, Collusi D, Espeseth AS, Lai MT, Pietrak BL, Holloway MK, McGaughey GB, Munshi SK, Hochman JH, Simon AJ, Selnick HG, Graham SL, Vacca JP. Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1788-92. Epub 2006 Dec 21. PMID:17257835 doi:10.1016/j.bmcl.2006.12.051