2aow: Difference between revisions

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{{Seed}}
[[Image:2aow.png|left|200px]]
[[Image:2aow.png|left|200px]]


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{{STRUCTURE_2aow|  PDB=2aow  |  SCENE=  }}  
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===Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===
===Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===


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{{ABSTRACT_PUBMED_16168438}}
{{ABSTRACT_PUBMED_16168438}}
==Disease==
Known disease associated with this structure: Asthma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605238 605238]]


==About this Structure==
==About this Structure==
2AOW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOW OCA].  
[[2aow]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOW OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:16168438</ref><references group="xtra"/>
<ref group="xtra">PMID:016168438</ref><references group="xtra"/>
[[Category: Histamine N-methyltransferase]]
[[Category: Histamine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Classic methyltransferase fold]]
[[Category: Classic methyltransferase fold]]
[[Category: Protein-drug complex]]
[[Category: Protein-drug complex]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:45:55 2009''

Revision as of 13:41, 6 January 2013

File:2aow.png

Template:STRUCTURE 2aow

Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug TacrineHistamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine

Template:ABSTRACT PUBMED 16168438

About this StructureAbout this Structure

2aow is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040

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