1zjk: Difference between revisions

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{{Seed}}
[[Image:1zjk.png|left|200px]]
[[Image:1zjk.png|left|200px]]


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{{ABSTRACT_PUBMED_16040602}}
{{ABSTRACT_PUBMED_16040602}}
==Disease==
Known disease associated with this structure: MASP2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605102 605102]]


==About this Structure==
==About this Structure==
1ZJK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZJK OCA].  
[[1zjk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZJK OCA].  


==Reference==
==Reference==
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[[Category: Zavodszky, P.]]
[[Category: Zavodszky, P.]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Hydrolase]]
[[Category: Modular protein]]
[[Category: Modular protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:20:31 2009''

Revision as of 23:03, 14 March 2011

File:1zjk.png

Template:STRUCTURE 1zjk

Crystal structure of the zymogen catalytic region of human MASP-2Crystal structure of the zymogen catalytic region of human MASP-2

Template:ABSTRACT PUBMED 16040602

About this StructureAbout this Structure

1zjk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Gal P, Harmat V, Kocsis A, Bian T, Barna L, Ambrus G, Vegh B, Balczer J, Sim RB, Naray-Szabo G, Zavodszky P. A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations. J Biol Chem. 2005 Sep 30;280(39):33435-44. Epub 2005 Jul 21. PMID:16040602 doi:10.1074/jbc.M506051200
  2. Harmat V, Gal P, Kardos J, Szilagyi K, Ambrus G, Vegh B, Naray-Szabo G, Zavodszky P. The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions. J Mol Biol. 2004 Oct 1;342(5):1533-46. PMID:15364579 doi:10.1016/j.jmb.2004.07.014

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