Lactose Permease: Difference between revisions
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These sidechains, which make up the active site of the protein, can be found within the large internal <scene name='Lactose_Permease/Cavity/2'>hydrophilic cavity</scene> of the lactose permease. It is here where the <scene name='Lactose_Permease/Sugar/2'>substrate</scene> is recieved for transport and it is the location from which it is deposited into the cell. The currently crystalized form of the permease is considered an 'inward-facing' conformation. This implies that the hydrophilic cavity mentioned previously is positioned with the opening towards the cytoplasm of the cell. Conversely, and outward-facing conformation would have the cavity facing the periplasm. | These sidechains, which make up the active site of the protein, can be found within the large internal <scene name='Lactose_Permease/Cavity/2'>hydrophilic cavity</scene> of the lactose permease. It is here where the <scene name='Lactose_Permease/Sugar/2'>substrate</scene> is recieved for transport and it is the location from which it is deposited into the cell. The currently crystalized form of the permease is considered an 'inward-facing' conformation. This implies that the hydrophilic cavity mentioned previously is positioned with the opening towards the cytoplasm of the cell. Conversely, and outward-facing conformation would have the cavity facing the periplasm. | ||
==<font color = 'red'>MSOE Center for BioMolecular Modeling</font>== | |||
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The physical models shown on this page were designed and built by the MSOE Center for BioMolecular Modeling. For more information about physical protein modeling, visit the CBM web site at [http://www.rpc.msoe.edu/cbm www.rpc.msoe.edu/cbm] . | |||