3ekk: Difference between revisions

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{{ABSTRACT_PUBMED_19056263}}
{{ABSTRACT_PUBMED_19056263}}
==Disease==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]


==About this Structure==
==About this Structure==
3EKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].  
3EKK is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].  


==Reference==
==Reference==
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase., Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB, Bioorg Med Chem Lett. 2008 Nov 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19056263 19056263]
<ref group="xtra">PMID:19056263</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Atkins, C.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Chamberlain, S.]]
[[Category: Deanda, F.]]
[[Category: Dumble, M.]]
[[Category: Gerding, R.]]
[[Category: Groy, A.]]
[[Category: Korenchuk, S.]]
[[Category: Kumar, R.]]
[[Category: Lei, H.]]
[[Category: Mook, R.]]
[[Category: Moorthy, G.]]
[[Category: Redman, A.]]
[[Category: Rowland, J.]]
[[Category: Sabbatini, P.]]
[[Category: Shewchuk, L.]]
[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]


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