1wae: Difference between revisions
New page: left|200px<br /> <applet load="1wae" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wae, resolution 1.95Å" /> '''CRYSTAL STRUCTURE O... |
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==About this Structure== | ==About this Structure== | ||
1WAE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | 1WAE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]] with CU and ZN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Transferred_entry:_1.7.2.1 Transferred entry: 1.7.2.1]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.99.3 1.7.99.3]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WAE OCA]]. | ||
==Reference== | ==Reference== | ||
Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15554622 15554622] | Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15554622 15554622] | ||
[[Category: | [[Category: Achromobacter xylosoxidans]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Transferred entry: 1.7.2.1]] | |||
[[Category: Antonyuk, S.V.]] | [[Category: Antonyuk, S.V.]] | ||
[[Category: Eady, R.R.]] | [[Category: Eady, R.R.]] | ||
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[[Category: reductase]] | [[Category: reductase]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:56:35 2007'' | ||
Revision as of 14:51, 30 October 2007
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CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE
OverviewOverview
Copper nitrite reductases contain both an electron-transfer type 1 Cu site, and a catalytic type 2 Cu site. We have mutated one of the type 2 copper, ligating histidines to observe the effect on catalytic turnover. This, mutation has created a unique site where Cu is ligated by 2 His Nepsilon2, atoms alone.
About this StructureAbout this Structure
1WAE is a [Single protein] structure of sequence from [Achromobacter xylosoxidans] with CU and ZN as [ligands]. Active as [Transferred entry: 1.7.2.1], with EC number [1.7.99.3]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:15554622
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