Sandbox108: Difference between revisions

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Glutamine synthetase from Salmonella typhimurium has 23 helix-helix interactions involving helices of chain A and four different types of interactions. [http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=2gls&template=protein.html&o=HELIX_INTERACTIONS&l=1&s=1&c=7&chain=A] Helix-helix interactions are the only interaction that can affect the folding of the proteins in Salmonella typhimurium. <scene name='Sandbox108/Hydrophobic/1'>Hydrophobic(purple)</scene> and <scene name='Sandbox108/Polar/1'>polar (blue)</scene> regions of the protein residues are on the helices of chain A. Also, uncharged polar groups are usually classified as hydrophilic that is found on the outside of proteins, but for glutamine in Salmonella typhimurium its side chain is uncharged and formed by replacing the hydroxyl of glutamic acid with an amine functional group. [http://en.wikipedia.org/wiki/Glutamine] Moreover, on the helices of chain A has <scene name='Sandbox108/Charged_region/1'>the charged regions</scene>.
Glutamine synthetase from Salmonella typhimurium has 23 helix-helix interactions involving helices of chain A and four different types of interactions. [http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=2gls&template=protein.html&o=HELIX_INTERACTIONS&l=1&s=1&c=7&chain=A] Helix-helix interactions are the only interaction that can affect the folding of the proteins in Salmonella typhimurium. <scene name='Sandbox108/Hydrophobic/1'>Hydrophobic(purple)</scene> and <scene name='Sandbox108/Polar/1'>polar(blue)</scene> regions of the protein residues are on the helices of chain A. Also, uncharged polar groups are usually classified as hydrophilic that is found on the outside of proteins, but for glutamine in Salmonella typhimurium its side chain is uncharged and formed by replacing the hydroxyl of glutamic acid with an amine functional group. [http://en.wikipedia.org/wiki/Glutamine] Moreover, on the helices of chain A has <scene name='Sandbox108/Charged_region/1'>the charged regions(blue and red)</scene>.

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Taewang Lee