2ze1: Difference between revisions
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[[Image:2ze1.png|left|200px]] | |||
[[Image:2ze1. | |||
{{STRUCTURE_2ze1| PDB=2ze1 | SCENE= }} | {{STRUCTURE_2ze1| PDB=2ze1 | SCENE= }} | ||
===X-ray structure of Bace-1 in complex with compound 6g=== | ===X-ray structure of Bace-1 in complex with compound 6g=== | ||
{{ABSTRACT_PUBMED_18162398}} | {{ABSTRACT_PUBMED_18162398}} | ||
==About this Structure== | ==About this Structure== | ||
[[2ze1]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZE1 OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018162398</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Olland, A.]] | [[Category: Olland, A.]] | ||
[[Category: Acylguanidine inhibitor]] | [[Category: Acylguanidine inhibitor]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace]] | [[Category: Bace]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 16:40, 25 July 2012
X-ray structure of Bace-1 in complex with compound 6gX-ray structure of Bace-1 in complex with compound 6g
Template:ABSTRACT PUBMED 18162398
About this StructureAbout this Structure
2ze1 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Cole DC, Stock JR, Chopra R, Cowling R, Ellingboe JW, Fan KY, Harrison BL, Hu Y, Jacobsen S, Jennings LD, Jin G, Lohse PA, Malamas MS, Manas ES, Moore WJ, O'Donnell MM, Olland AM, Robichaud AJ, Svenson K, Wu J, Wagner E, Bard J. Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1063-6. Epub 2007 Dec 10. PMID:18162398 doi:S0960-894X(07)01454-0