2zvt: Difference between revisions
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===Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2=== | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | <!-- | ||
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{{ABSTRACT_PUBMED_19101554}} | |||
==Disease== | |||
Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Insulin resistance, severe, digenic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Lipodystrophy, familial partial, type 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, severe OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Diabetes, type 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Glioblastoma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]] | |||
==About this Structure== | |||
2ZVT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVT OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19101554</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Morikawa, K.]] | |||
[[Category: Oyama, T.]] | |||
[[Category: Shiraki, T.]] | |||
[[Category: Waku, T.]] | |||
[[Category: Activator]] | |||
[[Category: Alternative splicing]] | |||
[[Category: Anti parallel helix sandwich]] | |||
[[Category: Diabetes mellitus]] | |||
[[Category: Disease mutation]] | |||
[[Category: Dna-binding]] | |||
[[Category: Metal-binding]] | |||
[[Category: Nucleus]] | |||
[[Category: Obesity]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Polymorphism]] | |||
[[Category: Receptor]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription regulation]] | |||
[[Category: Zinc]] | |||
[[Category: Zinc-finger]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:53:39 2009'' | |||
Revision as of 14:53, 7 October 2009
Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
Template:ABSTRACT PUBMED 19101554
DiseaseDisease
Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[601487], Insulin resistance, severe, digenic OMIM:[601487], Lipodystrophy, familial partial, type 3 OMIM:[601487], Obesity, severe OMIM:[601487], Obesity, resistance to OMIM:[601487], Diabetes, type 2 OMIM:[601487], Glioblastoma, susceptibility to OMIM:[601487]
About this StructureAbout this Structure
2ZVT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Waku T, Shiraki T, Oyama T, Morikawa K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 2009 Jan 22;583(2):320-4. Epub 2008 Dec 26. PMID:19101554 doi:10.1016/j.febslet.2008.12.017
Page seeded by OCA on Wed Oct 7 13:53:39 2009