3f5p: Difference between revisions

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New page: '''Unreleased structure''' The entry 3f5p is ON HOLD until Paper Publication Authors: Miller, L.M., Mayer, S.C., Xu, W., Berger, D.M., Boschelli, D.H., Boschelli, F., Di, L., Du, X., Du...
 
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'''Unreleased structure'''
{{Seed}}
[[Image:3f5p.jpg|left|200px]]


The entry 3f5p is ON HOLD until Paper Publication
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{{STRUCTURE_3f5p|  PDB=3f5p  |  SCENE=  }}


Authors: Miller, L.M., Mayer, S.C., Xu, W., Berger, D.M., Boschelli, D.H., Boschelli, F., Di, L., Du, X., Dutia, M., Floyd, M.B.
===Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor===


Description: Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:43:10 2008''
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{{ABSTRACT_PUBMED_19041240}}
 
==Disease==
Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147370 147370]]
 
==About this Structure==
3F5P is a 16 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5P OCA].
 
==Reference==
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W, Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. Epub 2008 Nov 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19041240 19041240]
 
Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18501599 18501599]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Berger, D M.]]
[[Category: Boschelli, D H.]]
[[Category: Boschelli, F.]]
[[Category: Mayer, S C.]]
[[Category: Miller, L M.]]
[[Category: Xu, W.]]
[[Category: Atp-binding]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Glycoprotein]]
[[Category: Igf-1r]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Receptor]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Tyrosine kinase]]
[[Category: Tyrosine-protein kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:36:35 2008''

Revision as of 11:36, 31 December 2008

File:3f5p.jpg

Template:STRUCTURE 3f5p

Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline InhibitorComplex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor

Template:ABSTRACT PUBMED 19041240

DiseaseDisease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147370]

About this StructureAbout this Structure

3F5P is a 16 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W, Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. Epub 2008 Nov 17. PMID:19041240

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599

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