3d0e: Difference between revisions
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[[Image:3d0e. | [[Image:3d0e.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
3D0E is a | 3D0E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0E OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18800763</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Concha, N O.]] | [[Category: Concha, N O.]] | ||
[[Category: Smallwood, A.]] | [[Category: Smallwood, A.]] | ||
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[[Category: Transferase inhibitor]] | [[Category: Transferase inhibitor]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:38:46 2009'' | ||
Revision as of 18:38, 17 February 2009
Crystal structure of human Akt2 in complex with GSK690693Crystal structure of human Akt2 in complex with GSK690693
Template:ABSTRACT PUBMED 18800763
DiseaseDisease
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]
About this StructureAbout this Structure
3D0E is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R. Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase. J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:18800763 doi:10.1021/jm8004527
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