3drs: Difference between revisions
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===HIV reverse transcriptase K103N mutant in complex with inhibitor R8D=== | ===HIV reverse transcriptase K103N mutant in complex with inhibitor R8D=== | ||
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{{ABSTRACT_PUBMED_18826204}} | |||
==About this Structure== | ==About this Structure== | ||
3DRS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRS OCA]. | 3DRS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRS OCA]. | ||
==Reference== | |||
Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses., Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Reid JC, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y, J Med Chem. 2008 Oct 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18826204 18826204] | |||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15: | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:58:49 2008'' | ||
Revision as of 16:58, 15 October 2008
HIV reverse transcriptase K103N mutant in complex with inhibitor R8DHIV reverse transcriptase K103N mutant in complex with inhibitor R8D
Template:ABSTRACT PUBMED 18826204
About this StructureAbout this Structure
3DRS is a Protein complex structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
ReferenceReference
Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses., Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Reid JC, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y, J Med Chem. 2008 Oct 1. PMID:18826204
Page seeded by OCA on Wed Oct 15 15:58:49 2008