Lac repressor: Difference between revisions

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Lac repressor binds to DNA non-specifically, enabling it to slide rapidly along the DNA double helix until it encounters the lac operator sequence. During <scene name='Lac_repressor/1osl_non-specific_binding/1'>non-specific binding</scene>, the <font color='orange'><b>hinge region</b></font> is disordered, and the<font color='#ae00ff'><b>DNA double helix</b></font> is straight.
Lac repressor binds to DNA non-specifically (<scene name='Lac_repressor/1osl_ca_dot_pdb/1'>initial scene</scene>, 20 [[NMR Ensembles of Models|NMR models]]), enabling it to slide rapidly along the DNA double helix until it encounters the lac operator sequence. During non-specific binding, the <font color='orange'><b>hinge region</b></font> is disordered (indicated by the range of positions of the 20 models), and the<font color='#ae00ff'><b>DNA double helix</b></font> is straight.


<scene name='Morphs/1osl_19_1l1m_9_morph/2'>morf</scene> 1osl_19_1l1m_9_morph.pdb
<scene name='Morphs/1osl_19_1l1m_9_morph/2'>morf</scene> 1osl_19_1l1m_9_morph.pdb

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Eran Hodis, David Canner, Michal Harel, Alexander Berchansky, Joel L. Sussman, Henry Jakubowski, Karsten Theis, Jaime Prilusky