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| ==About this Structure== | | ==About this Structure== |
| 1WV1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WV1 OCA]. | | 1WV1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WV1 OCA]. |
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| ==Reference== | | ==Reference== |
| Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs., Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E, Protein Sci. 2005 Jul;14(7):1760-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15987904 15987904]
| | <ref group="xtra">PMID:15987904</ref><ref group="xtra">PMID:16190745</ref><ref group="xtra">PMID:9384557</ref><ref group="xtra">PMID:10548038</ref><ref group="xtra">PMID:15214781</ref><references group="xtra"/> |
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| Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes., Klabunde T, Wendt KU, Kadereit D, Brachvogel V, Burger HJ, Herling AW, Oikonomakos NG, Kosmopoulou MN, Schmoll D, Sarubbi E, von Roedern E, Schonafinger K, Defossa E, J Med Chem. 2005 Oct 6;48(20):6178-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16190745 16190745]
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| The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor., Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN, Structure. 1997 Nov 15;5(11):1413-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9384557 9384557]
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| Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate., Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H, Protein Sci. 1999 Oct;8(10):1930-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10548038 10548038]
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| Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site., Kristiansen M, Andersen B, Iversen LF, Westergaard N, J Med Chem. 2004 Jul 1;47(14):3537-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15214781 15214781]
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| [[Category: Oryctolagus cuniculus]] | | [[Category: Oryctolagus cuniculus]] |
| [[Category: Phosphorylase]] | | [[Category: Phosphorylase]] |
| [[Category: Single protein]]
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| [[Category: Chrysina, E D.]] | | [[Category: Chrysina, E D.]] |
| [[Category: Defossa, E.]] | | [[Category: Defossa, E.]] |
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| [[Category: Type 2 diabetes]] | | [[Category: Type 2 diabetes]] |
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 01:12:02 2008'' | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:58:32 2009'' |