2qc8: Difference between revisions

Revision as of 17:40, 17 February 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2qc8.png

2qc8, resolution 2.60Å ()

Ligands:

, , ,

Gene:

GLUL, GLNS (Homo sapiens)

Activity:

Glutamate--ammonia ligase, with EC number 6.3.1.2

Related:

2ojw

Structural annotation:
Resources:	InterPro : Ipr014746, Ipr008147, Ipr008146 Pfam : PF00120, PF03951 UniProt : P15104

Functional annotation:
Cellular component:	cytoplasm
Biological process:	nitrogen compound metabolic process glutamine biosynthetic process regulation of neurotransmitter levels
Molecular function:	ligase activity glutamate-ammonia ligase activity catalytic activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphateCrystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate

Template:ABSTRACT PUBMED 18005987

About this StructureAbout this Structure

2QC8 is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. J Mol Biol. 2008 Jan 4;375(1):217-28. Epub 2007 Oct 17. PMID:18005987 doi:10.1016/j.jmb.2007.10.029

Page seeded by OCA on Tue Feb 17 16:40:26 2009

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. J Mol Biol. 2008 Jan 4;375(1):217-28. Epub 2007 Oct 17. PMID:18005987 doi:10.1016/j.jmb.2007.10.029

[xtra 1]

@@ Line 20: / Line 20: @@
 ==About this Structure==
-QC8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QC8 OCA].
+QC8 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QC8 OCA].
 ==Reference==
-Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design., Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL, J Mol Biol. 2008 Jan 4;375(1):217-28. Epub 2007 Oct 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18005987 18005987]
+<ref group="xtra">PMID:18005987</ref><references group="xtra"/>
 [[Category: Glutamate--ammonia ligase]]
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
 [[Category: Arrowsmith, C H.]]
 [[Category: Berg, S Van Den.]]
@@ Line 61: / Line 60: @@
 [[Category: Synthetase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:24:23 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:40:26 2009''