2p3t: Difference between revisions

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==About this Structure==
==About this Structure==
2P3T is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3T OCA].  
2P3T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3T OCA].  


==Reference==
==Reference==
Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors(1)., Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ, J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17536795 17536795]
<ref group="xtra">PMID:17536795</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Adler, M.]]
[[Category: Adler, M.]]
[[Category: Whitlow, M.]]
[[Category: Whitlow, M.]]
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[[Category: Protein inhibitor complex]]
[[Category: Protein inhibitor complex]]


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Revision as of 13:34, 17 February 2009

File:2p3t.png

Template:STRUCTURE 2p3t

Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amideCrystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide

Template:ABSTRACT PUBMED 17536795

About this StructureAbout this Structure

2P3T is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors(1). J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31. PMID:17536795 doi:10.1021/jm070125f

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