2qe2: Difference between revisions

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==About this Structure==
==About this Structure==
2QE2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QE2 OCA].  
2QE2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QE2 OCA].  


==Reference==
==Reference==
Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase., Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J, J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17402724 17402724]
<ref group="xtra">PMID:17402724</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Single protein]]
[[Category: Bard, J.]]
[[Category: Bard, J.]]
[[Category: Chopra, R.]]
[[Category: Chopra, R.]]
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[[Category: Transferase]]
[[Category: Transferase]]


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Revision as of 15:36, 16 February 2009

File:2qe2.png

Template:STRUCTURE 2qe2

Structure of HCV NS5B Bound to an Anthranilic Acid InhibitorStructure of HCV NS5B Bound to an Anthranilic Acid Inhibitor

Template:ABSTRACT PUBMED 17402724

About this StructureAbout this Structure

2QE2 is a 2 chains structure of sequences from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase. J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:17402724 doi:10.1021/jm061428x

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